In a very lengthy article found online at The Star Online, the author, Dr Milton Lum, a member of the board of Medical Defence Malaysia, gives his opinion on the highly controversial vaccination for HPV, Human papillomavirus.
Dr. Lum focuses on several aspects of the virus and vaccine in the article. He also discusses safety, effectiveness, vaccination for males, and sexual activity.
He begins the article by stating, “Based on current evidence, the benefits of HPV immunization far outweigh the risks, which are minimal.”
The human papillomavirus (HPV) vaccine which helps in the prevention of HPV infection, a leading causative factor of genital warts and cervical cancer, became available in 2006.
Although Malaysia started its national HPV vaccination program in 2010, certain quarters still have reservations. He states, “This article was written to enable parents and vaccinees to make an informed decision.”
Human papillomavirus (HPV), a DNA virus, is a common sexually transmitted infection. There are different HPV types. The cutaneous types cause non-cancerous warts (papillomas), which affect the hands and feet. These types differ from the mucosal types that affect the mouth, respiratory tract, and genitalia.
Many HPV types are transmitted sexually. The low risk types, HPV 6 and 11, cause benign genital warts and recurrent respiratory papillomas, while persistent infection with high-risk types, HPV 16 & 18, is associated with an increased risk of developing high grade cervical intraepithelial neoplasia (CIN), which is a precursor of cervical cancer.
HPV is a major cause of genital warts and cervical cancer. HPV infections by the high risk types are common in young, sexually active women and men. Most clear spontaneously without ever causing CIN, while some develop a persistent infection. Hence, cervical cancer is considered a rare consequence of persistent infection with one or more high risk types, with other factors playing a role.
HPV 16 and 18 together account for up to 70% of cervical cancers across the world. Other high risk types like HPV 31, 33 and 45, are also associated with cervical cancer.
HPV infections are more likely to occur in people who have more than one sexual partner or whose sexual partner has more than one partner.
Factors like smoking, multiple sexual partners, having many children, oral contraceptive use and HIV infection are associated with an increase in the risk of developing cervical cancer.
HPV also causes cancers of the vulva, vagina and anus. As HPV may have no symptoms, it may be more common than is thought.
There are two types HPV vaccines, bivalent (HPV 16 and 18) and quadrivalent vaccines (HPV 6, 11, 16 and 18). Both contain inactivated extracts from HPV. This means that it does not cause HPV or any conditions that HPV causes. Both vaccines provide protection against 70% of the HPV types that cause cervical cancer.
In addition, the quadrivalent vaccine also provides protection against 90% of the HPV types that cause genital warts, and HPV types that cause cancers of the vulva, vagina and anus.
HPV vaccines do not provide protection against the HPV types that a person has been exposed to. However, a person who has had HPV may still benefit from the vaccine because most people are not infected with all the types of HPV contained in the vaccine.
HPV vaccines also do not provide protection against other sexually transmitted infections (STI). This means that even after vaccination, safe sexual practices, including the use of condoms, are needed to prevent STIs.
He ends the section on the vaccine by saying, “HPV vaccination is no substitute for cervical screening. Those who have received HPV vaccines should continue cervical screening.”
To read more Dr. Lum‘s opinions, that include sections on safety, effectiveness, male vaccination and sexual activity, please visit the article here.